Beatriz María Cruz Yero
e-mail: beatrizm@cim.sld.cu / betyjuank@gmail.com
PROFESSIONAL SUMMARY
Master in Biotechnology with over 8 years of experience in the research, development, and innovation of monoclonal antibodies and therapeutic vaccines for the treatment of cancer and chronic non-communicable diseases. Specialist in Biological Assays. Head of Quality Control at the Center of Molecular Immunology (Biocubafarma, Havana, Cuba). Candidate for a Doctorate in fields related to Cellular and Molecular Biology or Neurosciences.
EDUCATION
Master's Degree in Contemporary Biotechnology, Quality Specialization (2025)
Center for Genetic Engineering and Biotechnology (CIGB)
Bachelor's Degree in Biology (2018)
University of Havana
PROFESSIONAL EXPERIENCE
Center of Molecular Immunology (Biocubafarma, Havana, Cuba)
09/2018 – 02/2024
Specialist in Physical Chemistry (Electrophoresis, spectrophotometry, ELISAs, pH)
Specialist in Biological Assays (Cell culture, flow cytometry, colorimetric assays)
Evaluation of stability studies and Reference Material characterization
01/2025 – Present
Head of Quality Control
TRAINING COURSES
03/2018 – Laboratory Animal Science (CIM, Havana, Cuba)
09/2018 – Good Laboratory Practice (GLP) (CIM, Havana, Cuba)
09/2018 – Good Manufacturing Practice (GMP) (CIM, Havana, Cuba)
10/2018 – Product Development (CIM, Havana, Cuba)
11/2018 – Advanced Topics in Immunology (Postgraduate) (CIM, Havana, Cuba)
03/2019 – Analytical Strategies for Biopharmaceutical Characterization (CIM, Havana, Cuba)
12/2019 – Tumor Biology (Postgraduate) (CIM, Havana, Cuba)
12/2019 – Vaccinology (Postgraduate) (CIM, Havana, Cuba)
03/2020 – Scientific Research Methodology (Postgraduate) (CIGB, Havana, Cuba)
04/2021 – Introduction to Contemporary Biotechnology (Postgraduate) (CIGB, Havana, Cuba)
07/2021 – Production Economics (Postgraduate) (CUJAE, Havana, Cuba)
09/2021 – Introduction to Molecular and Cellular Biology and Immunology (Postgraduate) (CIGB, Havana, Cuba)
01/2023 – Production Management (Postgraduate) (CUJAE, Havana, Cuba)
06/2025 – Assay Development and Validation (CIM, Havana, Cuba)
12/2025 – Introductory Course for Standard Practice (GxP) (GTHB/IVI, Republic of Korea)
CONFERENCES
10/2022-10/2022
International Biomanufacturing Challenges of Immunotherapy
Matanzas, Cuba
Cruz B.M., Solozabal J.A., Rivas G., Gómez T., Gómez J.A. (2023). Stress stability study of the IL2 non-alpha mutein
05/2023-05/2023
5th International Congress of Research, Development and Innovation in the Biopharmaceutical Industry, IDIFARMA 2023
Havana, Cuba
Cruz B.M., Cedeño A. M., Diaz G. W. (2023). Development of the biological activity assay for anti-NGcGM3 mAb. Preliminary results.
Solozabal J.A., Cruz B.M. Development of two interaction analysis methods by SPR technology as QC releasing techniques for HER1-ECD cell banks
10/2024-10/2024
International Biomanufacturing Challenges of Immunotherapy
Matanzas, Cuba
Cruz B.M., Ge A., Cedeño A. M., Peña V. (2024). TF1 Cell proliferation assay for estimating bioactivity of NeuroEPO
PUBLICATIONS
- Casadesús A.V., Cruz B.M., Diaz G. W., González M. A., Gómez T., Fernández B., González A., Ledón N., Sosa K., Castro K., López A., Plasencia C., Ramírez Y., Teillaud J. L., Hernández C., León K., Hernández T. (2022). Potent immunomodulatory and antitumor effect of anti-CD20-IL2no-alpha tri-functional immunocytokine for cancer therapy. Frontiers in Immunology, 13:1021828. DOI: 10.3389/fimmu.2022.1021828.
- Cruz B.M., Ge A., Cedeño M., Peña V., Rodríguez T. (2026). Evaluation of the TF1 cell line as a biomodel for estimating the biological activity of NeuroEPO. Revista Cubana de Investigaciones Biomédicas, 45:3786.
LANGUAGES
English: Intermediate
Spanish: Native